The Nightshade Sanctuary was a large ancient ruined sanctuary located in the wild forests of Eriador. The Nightshade Crypt is located underneath the sanctuary. This was the home of a human clan known as Nightshade Warriors, The clan was founded by Warlord Guldar in the end of the First Age.
After centuries of war against rival clans, the Nightshade Sanctuary finally fell to the clan known as Steel-Hearts in the middle of the Second Age, who layed siege on the sanctuary and killed everyone in the sanctuary and burned the place down. The sanctuary eventually collapsed, the tomb underneath the sanctuary was also burned down and collapsed, the corpses of the warriors were abandoned in the ruin. Many years later, in TA 2994, The ruins were cleansed of undead by Hogin Wolf-Claw.